What is RU58841?
RU58841 is an androgen receptor antagonist. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia (pattern baldness) and acne. In studies and clinical trials RU58841 has shown to strongly compete against DHT at the androgen receptor. The researchers noted that topical application of RU58841 at the test subject increased the hair densitity, increased the percentage of hair in the anagen phase and provided a better netto growth of hair.
What Are Essential Oils?
Essential oils are proven to help against hair loss. Our solutions that are enriched with essential oils, will increase circulation in the scalp similar to the effects of Minoxidil, but without a shedding phase and other Minoxidil related side effects. Our solution contain pepermint oil, tea tree oil and lavender oil. These essential oils alone work great for reducing hair loss and recude scalp inflammation. The combined oils make a synergic effect, that will calm down the inflammed scalp, increase circulation and stimulate hair follicles. When applied, the scalp will immediately feel calmed down, due to the cooling and inflammation reducing effect of essential oils.
What is OctoPirox (Piroctone Olamine)?
OctoPirox, also known as piroctone olamine, is a chemical very much related to ketoconazole. It has proven its effeciacy in various studies. One of these studies is summarized here below.
A study of 150 men with androgenic alopecia and dandruff compared Ketoconazole and Piroctone Olamine. Excessive sebum secretion, dandruff and seborrheic eczema are often associated with hair loss and androgenic alopecia. The 150 men were given a shampoo containing 1% Ketoconazole or 1% Piroctone Olamine. They had to use this shampoo 2-3 times a week for six months.
Both treatments showed a reduction in itching and dandruff after two to six weeks. Looking at the effect of the treatments on different hair growth parameters, the following figures (in percentages) can be seen:
- Hair loss decreases: (Ketoconazole: -17.3%, Piroctone Olamine: -16.5%)
- The percentage of hair in the growth phase increases: (Ketoconazole 4.9%, Piroctone Olamine: 7.9%).
- The hair diameter increases: (5.4% increase with Ketoconazole and 7.7% with Piroctone Olamine)
- The study thus shows that Piroctone Olamine scores better than Ketoconazole on a number of levels.
Compared with Ketoconazole, Piroctone Olamine increases the number of hairs in the growth phase (anagen phase) by more than 10% in 33% more people.
With Piroctone Olamine, 88% of people get increased hair thickness, despite androgenic alopecia, whereas with Ketoconazole this is 78%.
Source: Pierard-Franchimont, C., Goffin, V., Henry, F., Uhoda, I., Braham, C., & Pierard, G.E. (2002). Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% Piroctone olamine and 1% zinc pyrithione formulations. International Journal of Cosmetic Science, 2002, 24, 249-256.
Other active ingredients:
Ginseng Extract, Natural Linalool, Biotin, Limonele
|Molecular Weight:||369.34 g/mol|
|Storage:||Liquids are stable up to 12 months in room temperature. In warm climates, store in the refrigerator. Unused raw powders are best stored in a zip lock bag in the freezer. Shelf life of properly stored raw materials: up to 36 months.|
3%, 5% (mostly used), 8%, 3% + Essential Oils, 5% + Essential Oils, 8% + Essential Oils, 3% + Essential Oils + OctoPirox, 5% + Essential Oils + OctoPirox, 8% + Essential Oils + OctoPirox