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Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.
It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased. The status of melanotan II is now classified as research chemical.
Melanotan II acts as a non-selective agonist of the melanocortin receptors MC1, MC3, MC4, and MC5.
Melanotan II produces melanogenesis by activation of the MC1 receptor, whereas its clinically documented sexual effects are thought to be related to its ability to activate the MC4 receptor (though the MC3 is thought to also possibly be involved).
Other effects of melanotan II, mostly regarded as adverse effects, include flushing, nausea, vomiting, stretching, yawning, and loss of appetite (the last via activation of MC4).
Did you know PT-141 is an isolated form of melanotan II? They isolated the arousal and sexual benefits and called it PT-141. You can check it here in our shop.
Intended for research use only
10 mg per vial.
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