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Pyrilutamide Powder – 500 mg (KX-826)


139.00 Inc. VAT


What is Pyrilutamide?

Pyrilutamide (KX-826) is a nonsteroidal anti androgen, or more specifically, a selective high-affinity silent antagonist of the androgen receptor, which is researched now for the potential treatment of androgenetic alopecia in males and females. Pyrilutamide binds to the androgen receptor with a very high affinity with an IC50 of 0.28nM.

Pyrilutamide has very similar properties as RU58841, but it is a way more refined and stronger version. Pyrilutamide is a very well tolerable, with very few systemic side effects. From anecdotal and indoor research, there were no significant side effects to note with dosages up to 5 mg per day, whilst hair loss was significantly reduced within the first week. This makes a huge promise for the treatment of androgenic alopecia, and specifically diffuse androgenic alopecia, which is a very hard to treat form of androgenic alopecia. Both RU58841 and pyrilutamide are very effective chemicals to stop hair loss from androgenic alopecia. As with everything, there is no one-size-fits all solution for androgenic alopecia, but pyrilutamide comes very close to this.

Q & A

Q: In what vehicle is the pyrilutamide dissolved?

A: The recommended solution to dissolve pyrilutamide powder in, is a Ethanol/PG solution.

Q: I need to cover my full scalp, but I can’t get it done with 1 ml (5mg).

A: We recommend to dilute the solution. So add 30 ml Ethanol/PG solution to your 0.5% pyrilutamide 30 ml solution. This will make a 60 ml pyrilutamide solution at 0.25% strength. For convenience, we recommend this 60 ml mixing bottle. Using 2 ml of the 0.25% strength should be enough to cover the full scalp, which is a total daily dose of 5 mg, which was used in the research papers.


Chemical Info

CAS Number: 1272719-00-2
Molecular Formula: C21H15F5N4O2S


Molecular Weight: 482.429 g/mol
Storage: Unused raw powders are best stored in a zip lock bag in the freezer (-19°C) for optimal shelf life (36 months). Raw powders stored in room temperature are stable up to 18 months. After 18 months the chemical will slowly degrade.

Safety Recommendations
Safety Measures: View
Material Safety Data Sheet: View 

4 reviews for Pyrilutamide Powder – 500 mg (KX-826)

  • Ahmad Salban

    September 11, 2022 at 1:54 pm

    5 out of 5

    Been using KX for about four weeks now. Hair fall decreased in the first days and stopped for 90% in approximately a week. Very amused with this. So far no side effects. With RU 58841 my libido decreases in a few days. Not having this problem now so I am happy. Greetings from Germany


    • Saverio

      September 14, 2022 at 9:00 am

      5 out of 5

      Which % of pyri are using? Everyday?


  • Paul

    September 25, 2022 at 6:59 am

    5 out of 5

    Is this supposed to be applied on the scalp like minoxidil or how does it work? I need instructions.


    • actifolic

      October 3, 2022 at 10:40 am

      It needs to be diluted with a pg/ethanol solution.


  • Javier

    September 27, 2022 at 8:40 pm

    5 out of 5

    Hi, Can kx 826 powders be diluted in your PG FREE solvent?


    • actifolic

      October 3, 2022 at 10:38 am

      Yes this is suitable.


  • Mathias S

    October 3, 2022 at 10:45 am

    5 out of 5

    Thank you so much. I only trust you guys and with this again i made a good choice. It’s working great man.


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